ResourcesPodcast

Do You Really Need an MBA to Work in Startups? A Pediatrician’s Path to VC + Founding Grapevyne
with Zhen Chan

Episode 51 · January 21, 2026 · 33 min

Hosted by Alison Curfman, MD

FundraisingCareer paths

Show notes

What does it actually take for a physician to break into startups or venture capital—and do you need an MBA to do it?

In this episode of Startup Physicians, Dr. Alison Curfman talks with Dr. Zhen Chan, a practicing pediatrician and founder of Grapevyne. Zhen shares how he moved from a traditional training path to venture work, what “due diligence” looks like in the real world, and why clinical insight is often the missing piece in healthcare products.

They also discuss why physicians often overvalue credentials, how networking creates opportunities faster than another degree, and how Zhen pivoted Grapevyne from a job marketplace into a community built to help clinicians expand their skills and impact in 2025 and beyond.

Takeaways

  • Zhen Chan transitioned from clinical medicine to startups.
  • Networking is crucial for career development in healthcare.
  • Experience can be more valuable than formal education.
  • Venture fellowships provide exposure to the startup ecosystem.
  • Clinical perspectives are essential in evaluating healthcare startups.
  • Grapevyne aims to empower physicians and medical professionals.
  • The importance of adaptability and pivoting in entrepreneurship.
  • Understanding regulatory pathways is vital for healthcare innovation.
  • Building a community can enhance professional growth.
  • Physicians have unique insights that can drive startup success.



Connect with Zhen: https://www.linkedin.com/in/zhenmd)
Learn more about Grapevyne: https://grapevyne.health)

https://instagram.com/zhen_md

https://www.tiktok.com/@zhenmd


Chapters

00:00Intro + Zhen’s background

01:30MBA vs real-world experience

03:10Why he pivoted from fellowship plans

05:55Networking as the unlock

12:05Venture fellowships + due diligence explained

16:10Unpaid roles, equity, and value exchange

21:05What he learned: how investors think

24:50The unique value of physician perspective

28:15What Grapevyne is building now

30:45Pivot story + closing